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Article

Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.

Psychosomatic medicine - 1 Apr 2018

Haljas Kadri, Amare Azmeraw T, Alizadeh Behrooz Z, Hsu Yi-Hsiang, Mosley Thomas, Newman Anne, Murabito Joanne, Tiemeier Henning, Tanaka Toshiko, van Duijn Cornelia, Ding Jingzhong, Llewellyn David J, Bennett David A, Terracciano Antonio, Launer Lenore, Ladwig Karl-Heinz, Cornelis Marylin C, Teumer Alexander, Grabe Hans, Kardia Sharon L R, Ware Erin B, Smith Jennifer A, Snieder Harold, Eriksson Johan G, Groop Leif, Räikkönen Katri, Lahti Jari

Abstract excerpt

OBJECTIVE: Shared genetic background may explain phenotypic associations between depression and Type 2 diabetes (T2D). We aimed to study, on a genome-wide level, if genetic correlation and pleiotropic loci exist between depressive symptoms and T2D or glycemic traits. METHODS: We estimated single-nucleotide polymorphism (SNP)-based heritability and analyzed genetic correlation between depressive symptoms and T2D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29280852
DOI: 10.1097/PSY.0000000000000555
PMCID: PMC6051528

Genes

CDKAL1
MADD
PEX16
PLEKHA1

Provenance

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