Article
Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity.
Biological psychiatry - 15 Jul 2018
Avinun Reut, Nevo Adam, Knodt Annchen R, Elliott Maxwell L, Hariri Ahmad R
Abstract excerpt
BACKGROUND: Low replication rates are a concern in most, if not all, scientific disciplines. In psychiatric genetics specifically, targeting intermediate brain phenotypes, which are more closely associated with putative genetic effects, was touted as a strategy leading to increased power and replicability. In the current study, we attempted to replicate previously published associations between single nucleotide...
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