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Article

Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans.

Molecular psychiatry - 1 Oct 2009

Meyer-Lindenberg A, Kolachana B, Gold B, Olsh A, Nicodemus K K, Mattay V, Dean M, Weinberger D R

Abstract excerpt

In mammals, the neuropeptide vasopressin is a key molecule for complex emotional and social behaviours. Two microsatellite polymorphisms, RS1 and RS3, near the promoter of AVPR1A, encoding the receptor subtype most heavily implicated in behaviour regulation, have been linked to autism and behavioural traits. However, the impact of these variants on human brain function is unknown. Here we show that human amygdala...

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Identifiers

PMID: 18490926
DOI: 10.1038/mp.2008.54
PMCID: PMC2754603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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