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Article

Reprogramming the Activatable Peptide Display Function of Adeno-Associated Virus Nanoparticles.

ACS nano - 27 Feb 2018

Thadani Nicole N, Dempsey Christopher, Zhao Julia, Vasquez Sonya M, Suh Junghae

Abstract excerpt

We harnessed an intrinsic activatable peptide display behavior shared by several parvoviruses, including the adeno-associated virus (AAV), in order to design protein-based nanodevices that can carry out an exogenous functional output in response to stimulus detection. Specifically, we generated truncated viral capsid subunits that, when combined with native capsid components into mosaic capsids, can perform...

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PMID: 29278489
DOI: 10.1021/acsnano.7b07804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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