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Article

Direct Detection of Drug-Resistant Hepatitis B Virus in Serum Using a Dendron-Modified Microarray.

Gut and liver - 15 May 2018

Kim Doo Hyun, Kang Hong Seok, Hur Seong-Suk, Sim Seobo, Ahn Sung Hyun, Park Yong Kwang, Park Eun-Sook, Lee Ah Ram, Park Soree, Kwon So Young, Lee Jeong-Hoon, Kim Kyun-Hwan

Abstract excerpt

BACKGROUND/AIMS: Direct sequencing is the gold standard for the detection of drug-resistance mutations in hepatitis B virus (HBV); however, this procedure is time-consuming, labor-intensive, and difficult to adapt to high-throughput screening. In this study, we aimed to develop a dendron-modified DNA microarray for the detection of genotypic resistance mutations and evaluate its efficiency. METHODS: The...

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Identifiers

PMID: 29271185
DOI: 10.5009/gnl17336
PMCID: PMC5945265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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