Article
Development of a high-throughput DNA microarray for drug-resistant gene detection and its preliminary application.
Journal of microbiological methods - 1 May 2012
Fu Yali, Pan Ying, Pan Mingjie, Wang Yao, Liu Wu, Li Yuexi
Abstract excerpt
Most bacteria are resistant to a wide variety of antibiotics and other drugs, which decrease the effectiveness of clinical drug therapies. The present study developed a high-throughput DNA microarray for drug-resistant gene detection. A total of 115 specific oligonuclieotide probes with lengths of 42 nt to 45 nt and comparable Tm values were selected from 17 categories of drug-resistant genes in the National...
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