Article

An RNA-based system to study hepatitis B virus replication and select drug-resistance mutations

2019-10-02

Abstract excerpt

Hepatitis B virus (HBV) chronically infects over 250 million people worldwide, increasing their risk of liver cirrhosis and hepatocellular carcinoma. There is a vaccine to prevent new infections, but no efficient cure for chronic infection. New insights into HBV biology are needed to improve cure rates for this widespread devastating disease. We describe a method to initiate replication of HBV, a DNA virus, using...

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Literature Corpus work: 60a5d1c3-eb40-5624-ada0-9b2b89b01533
DOI: 10.1101/787630

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