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Article

An improved reverse dot hybridization for simple and rapid detection of adefovir dipivoxil-resistant hepatitis B virus.

Genetics and molecular research : GMR - 9 Jan 2012

Hu Y, Zhang W L, Xie S L, Zhao Y, Hu J L, Cai X F, Lai G Q, Huang A L

Abstract excerpt

Early detection of adefovir dipivoxil-resistant mutants during long-term treatment of chronic hepatitis B virus (HBV) infection with this drug is of great clinical importance. We developed an improved reverse dot hybridization test for simple and rapid detection of the rtA181V/T and rtN236T mutations associated with adefovir dipivoxil resistance in chronic hepatitis B patients. Probes were designed for...

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Identifiers

PMID: 22290465
DOI: 10.4238/2012.January.9.6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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