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Article

Modeling pathogenesis and treatment response in childhood absence epilepsy

18 Dec 2017

Abstract excerpt

Summary Objective Childhood absence epilepsy (CAE) is a genetic generalized epilepsy syndrome with polygenic inheritance, with genes for γ‐aminobutyric acid (GABA) receptors and T‐type calcium channels implicated in the disorder. Previous studies of T‐type calcium channel electrophysiology have shown genetic changes and medications have multiple effects. The aim of this study was to use an established...

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PMID: 29265352
DOI: 10.1111/epi.13962

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