Article
ABCG transporters and disease.
The FEBS journal - 1 Sept 2011
Woodward Owen M, Köttgen Anna, Köttgen Michael
Abstract excerpt
ATP-binding cassette (ABC) transporters form a large family of transmembrane proteins that facilitate the transport of specific substrates across membranes in an ATP-dependent manner. Transported substrates include lipids, lipopolysaccharides, amino acids, peptides, proteins, inorganic ions, sugars and xenobiotics. Despite this broad array of substrates, the physiological substrate of many ABC transporters has...
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