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Article

The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis.

Cell reports - 19 Dec 2017

Goupille Olivier, Penglong Tipparat, Kadri Zahra, Granger-Locatelli Marine, Denis Raphaël, Luquet Serge, Badoual Cécile, Fucharoen Suthat, Maouche-Chrétien Leila, Leboulch Philippe, Chrétien Stany

Abstract excerpt

GATA transcription factors and their FOG cofactors play a key role in tissue-specific development and differentiation, from worms to humans. Mammals have six GATA and two FOG factors. We recently demonstrated that interactions between retinoblastoma protein (pRb) and GATA-1 are crucial for erythroid proliferation and differentiation. We show here that the LXCXE pRb-binding site of FOG-2 is involved in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29262331
DOI: 10.1016/j.celrep.2017.11.098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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