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Article

Friend of GATA-1-independent transcriptional repression: a novel mode of GATA-1 function.

Blood - 15 Jun 2007

Johnson Kirby D, Boyer Meghan E, Kang Jeong-Ah, Wickrema Amittha, Cantor Alan B, Bresnick Emery H

Abstract excerpt

The GATA-1-interacting protein Friend Of GATA-1 (FOG-1) is essential for the proper transcriptional activation and repression of numerous GATA-1 target genes. Although FOG-1-independent activation by GATA-1 has been described, all known examples of GATA-1-mediated repression are FOG-1 dependent. In the GATA-1-null G1E cell line, estrogen receptor ligand binding domain (ER) chimeras of either wild-type GATA-1 or a...

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Identifiers

PMID: 17339418
DOI: 10.1182/blood-2007-02-072983
PMCID: PMC1890840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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