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Article

FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development.

Developmental biology - 1 Nov 2014

Garnatz Audrey S, Gao Zhiguang, Broman Michael, Martens Spencer, Earley Judy U, Svensson Eric C

Abstract excerpt

FOG-2 is a multi-zinc finger protein that binds the transcriptional activator GATA4 and modulates GATA4-mediated regulation of target genes during heart development. Our previous work has demonstrated that the Nucleosome Remodeling and Deacetylase (NuRD) complex physically interacts with FOG-2 and is necessary for FOG-2 mediated repression of GATA4 activity in vitro. However, the relevance of this interaction for...

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Identifiers

PMID: 25196150
DOI: 10.1016/j.ydbio.2014.08.030
PMCID: PMC4190033

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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