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ConsensusDriver Improves upon Individual Algorithms for Predicting Driver Alterations in Different Cancer Types and Individual Patients.

Cancer research - 1 Jan 2018

Bertrand Denis, Drissler Sibyl, Chia Burton K, Koh Jia Yu, Li Chenhao, Suphavilai Chayaporn, Tan Iain Beehuat, Nagarajan Niranjan

Abstract excerpt

Existing cancer driver prediction methods are based on very different assumptions and each of them can detect only a particular subset of driver genes. Here we perform a comprehensive assessment of 18 driver prediction methods on more than 3,400 tumor samples from 15 cancer types, all to determine their suitability in guiding precision medicine efforts. We categorized these methods into five groups: functional...

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PMID: 29259006
DOI: 10.1158/0008-5472.CAN-17-1345

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INA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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