Article
Metabolic phenotyping of human atherosclerotic plaques: Metabolic alterations and their biological relevance in plaque-containing aorta.
Atherosclerosis - 1 Feb 2018
Jung Sunhee, Song Suk-Won, Lee Sak, Kim Se Hoon, Ann Soo-Jin, Cheon Eun Jeong, Yi Gijong, Choi Eui-Young, Lee Seung Hyun, Joo Hyun-Chel, Ryu Do Hyun, Lee Sang-Hak, Hwang Geum-Sook
Abstract excerpt
BACKGROUND AND AIMS: Atherosclerosis is a chronic inflammatory disease characterized by thickening of the arterial wall. However, a limited number of studies have been conducted on metabolic profiling of human aortic tissue. METHODS: We applied liquid chromatography/mass spectrometry to perform global and targeted profiling of plaque-containing aortic tissue. The aorta samples included plaque-containing (n = 18)...
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