Article
NG2 and GFAP co-expression after differentiation in cells transfected with mutant GFAP and in undifferentiated glioma cells.
Neurologia - 1 Sept 2020
Gómez-Pinedo U, Sirerol-Piquer S, Durán-Moreno M, Matias-Guiu J A, Barcia J A, García-Verdugo J M, Matias-Guiu J
Abstract excerpt
INTRODUCTION: Alexander disease is a rare disorder caused by mutations in the gene coding for glial fibrillary acidic protein (GFAP). In a previous study, differentiation of neurospheres transfected with these mutations resulted in a cell type that expresses both GFAP and NG2. OBJECTIVE: To determine the effect of molecular marker mutations in comparison to undifferentiated glioma cells simultaneously expressing...
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