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Article

Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation.

Stem cells and development - 1 Jul 2010

Kaus Aljoscha, Widera Darius, Kassmer Susannah, Peter Jan, Zaenker Kurt, Kaltschmidt Christian, Kaltschmidt Barbara

Abstract excerpt

One of the challenges in stem cell research is to avoid transformation during cultivation. We studied high passage subventricular zone derived neural stem cells (NSCs) cultures of adult rats in the absence of growth factors epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF)....

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PMID: 20184430
DOI: 10.1089/scd.2009.0416

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20184430-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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