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Article

A vicious interplay between genetic and environmental insults in the etiology of blood cancers.

Experimental hematology - 1 Mar 2018

Migliaccio Anna Rita

Abstract excerpt

Over the years, the etiology of cancer has been attributed alternatively to genetic and environmental insults. According to the genetic hypothesis, cancer cells arise from the acquisition of mutations that dysregulate the intrinsic mechanisms controlling normal cell growth and survival. In contrast, the environmental hypothesis holds that cancer can be caused by multiple extrinsic challenges that alter normal...

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Source

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Identifiers

PMID: 29248611
DOI: 10.1016/j.exphem.2017.12.004
PMCID: PMC6381597

Genes

TNF
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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