Article
Human Chitotriosidase Does Not Catabolize Hyaluronan.
International journal of biological macromolecules - 1 Apr 2018
Danielson Ben, Chen Che-Hong, Kaber Gernot, Mochly-Rosen Daria, Grimes Kevin, Stern Robert, Bollyky Paul L
Abstract excerpt
Humans express an enzyme that degrades chitin, called chitotriosidase, despite the fact that we do not produce chitin. One possible explanation for this is that chitinase also degrades hyaluronan, a polysaccharide that is abundant in human tissues and shares structural attributes in common with chitinase. The objective of this study was to determine whether human chitotriosidase is capable of hydrolyzing...
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