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Article

Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases.

Genetics - 1 Oct 2007

Bussink Anton P, Speijer Dave, Aerts Johannes M F G, Boot Rolf G

Abstract excerpt

Family 18 of glycosyl hydrolases encompasses chitinases and so-called chi-lectins lacking enzymatic activity due to amino acid substitutions in their active site. Both types of proteins widely occur in mammals although these organisms lack endogenous chitin. Their physiological function(s) as well as evolutionary relationships are still largely enigmatic. An overview of all family members is presented and their...

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Source

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Identifiers

PMID: 17720922
DOI: 10.1534/genetics.107.075846
PMCID: PMC2034658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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