Article
De novo recipient-specific Glutathione S-transferase T1 antibody development after HLA-identical hematopoietic cell transplantation.
Transplant immunology - 1 Feb 2018
Martínez-Bravo María José, Sánchez Berta, Acevedo María José, Pérez-Simón José Antonio, Núñez-Roldán Antonio, Aguilera Isabel
Abstract excerpt
Donor-specific antibodies against Glutathione S-transferase T1 (GSTT1) have been associated with de novo immune hepatitis after liver transplantation. These antibodies have also been found very early in allo-HCT associated with acute hepatic GvHD but in all the cases the donor cells had experienced previous priming through pregnancies. It remained to be explored whether or not primary recognition of the antigen...
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