Article
Anti-glutathione S-transferase T1 antibody-mediated rejection in C4d-positive renal allograft recipients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2008
Aguilera Isabel, Alvarez-Marquez Antonia, Gentil Miguel Angel, Fernandez-Alonso Jorge, Fijo Julia, Saez Carmen, Wichmann Ingeborg, Nuñez-Roldan Antonio
Abstract excerpt
BACKGROUND: Chronic humoral rejection is a progressive form of graft injury, with defined diagnostic criteria, the crucial one being the evidence of circulating anti-donor antibodies. These antibodies are mainly directed against human leucocyte antigens (HLA), but other targets have also been described. We previously reported that antibodies against the Glutathione S-transferase T1 (GSTT1) enzyme appear in...
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