Article
Antibodies against glutathione S-transferase T1 (GSTT1) in patients with de novo immune hepatitis following liver transplantation.
Clinical and experimental immunology - 1 Dec 2001
Aguilera I, Wichmann I, Sousa J M, Bernardos A, Franco E, García-Lozano J R, Núñez-Roldán A
Abstract excerpt
Four patients of 283 liver-transplant recipients (1.4%) developed de novo immune-mediated hepatitis approximately 2 years after transplantation. Antibodies showing an unusual liver/kidney cytoplasmic staining pattern were detected in the sera of all four patients and one of them was used to screen a human liver cDNA expression library with the aim of identifying the antigenic target of these newly developed...
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