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Article

Febrile temperature reprograms by redox-mediated signaling the mitochondrial metabolic phenotype in monocyte-derived dendritic cells.

Biochimica et biophysica acta. Molecular basis of disease - 1 Mar 2018

Menga Marta, Trotta Rosa, Scrima Rosella, Pacelli Consiglia, Silvestri Veronica, Piccoli Claudia, Capitanio Nazzareno, Liso Arcangelo

Abstract excerpt

Fever-like hyperthermia is known to stimulate innate and adaptive immune responses. Hyperthermia-induced immune stimulation is also accompanied with, and likely conditioned by, changes in the cell metabolism and, in particular, mitochondrial metabolism is now recognized to play a pivotal role in this context, both as energy supplier and as signaling platform. In this study we asked if challenging human...

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Identifiers

PMID: 29246446
DOI: 10.1016/j.bbadis.2017.12.010

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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