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Article

A novel DMAPP-responding genetic circuit sensor for high-throughput screening and evolving isoprene synthase.

Applied microbiology and biotechnology - 1 Feb 2018

Liu Chun-Li, Cai Jing-Yi, Bi Hao-Ran, Tan Tian-Wei

Abstract excerpt

High-throughput screening is a popular tool for collating biological data which would otherwise require the use of excessive resources. In this study, an artificial genetic circuit sensor responding to dimethylallyl diphosphate (DMAPP) was constructed based on a modified L-arabinose operon for high-throughput screening and isoprene synthase (ispS) evolution in Escherichia coli (E. coli). As a first step, the DNA...

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PMID: 29243081
DOI: 10.1007/s00253-017-8676-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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