Article
Construction of a genetic multiplexer to toggle between chemosensory pathways in Escherichia coli.
Journal of molecular biology - 18 Feb 2011
Moon Tae Seok, Clarke Elizabeth J, Groban Eli S, Tamsir Alvin, Clark Ryan M, Eames Matthew, Kortemme Tanja, Voigt Christopher A
Abstract excerpt
Many applications require cells to switch between discrete phenotypic states. Here, we harness the FimBE inversion switch to flip a promoter, allowing expression to be toggled between two genes oriented in opposite directions. The response characteristics of the switch are characterized using two...
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