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Article

Construction of a genetic multiplexer to toggle between chemosensory pathways in Escherichia coli.

Journal of molecular biology - 18 Feb 2011

Moon Tae Seok, Clarke Elizabeth J, Groban Eli S, Tamsir Alvin, Clark Ryan M, Eames Matthew, Kortemme Tanja, Voigt Christopher A

Abstract excerpt

Many applications require cells to switch between discrete phenotypic states. Here, we harness the FimBE inversion switch to flip a promoter, allowing expression to be toggled between two genes oriented in opposite directions. The response characteristics of the switch are characterized using two-color cytometry. This switch is used to toggle between orthogonal chemosensory pathways by controlling the expression...

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Identifiers

PMID: 21185306
DOI: 10.1016/j.jmb.2010.12.019
PMCID: PMC3033806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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