Article
Interferon lambda4 polymorphism is not associated with human papillomavirus infection outcome.
Virus genes - 1 Apr 2018
Cannella Fabiana, Scagnolari Carolina, Statzu Maura, Sciandra Ilaria, Recine Nadia, d'Ettorre Gabriella, Antonelli Guido, Pierangeli Alessandra
Abstract excerpt
Interferon (IFN) lambdas are important specific components of the mucosal innate immune response. The IFN lambda 4 (IFNL4) dinucleotide polymorphism (ΔG/TT) determines the IFN lambdas and related Interferon-stimulated genes activation, in HCV and other chronic infections. Our group first reported that IFN Lambda response was impaired in high-risk Human Papillomavirus (HPV) cervical infections and in precancerous...
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