Article
IFN-gamma and IL-12B polymorphisms in women with cervical intraepithellial neoplasia caused by human papillomavirus.
Molecular biology reports - 1 Jul 2012
do Carmo Vasconcelos de Carvalho Viviane, de Macêdo Jamilly Lopes, de Lima Camilla Albertina Dantas, da Conceição Gomes de Lima Maria, de Andrade Heráclio Sandra, Amorim Melânia, de Mascena Diniz Maia Maria, Porto Ana Lúcia Figueiredo, de Souza Paulo Roberto Eleutério
Abstract excerpt
The Human Papillomavirus (HPV) is a sexually transmitted organism associated with Cervical Intraepithelial Neoplasia (CIN) and cervical cancer, the second main cause of malignancy in women worldwide. The virus itself, however, is not enough to cause lesions on the cervix. Several studies suggest that some polymorphic sites changes the cytokines levels and influence the cancer development in HPV infected patients....
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