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Article

Interferon gamma +874 T/A polymorphism contributes to cancer susceptibility: a meta-analysis based on 17 case-control studies.

Molecular biology reports - 1 Oct 2011

Mi Yuan-Yuan, Yu Qian-Qian, Xu Bin, Zhang Li-Feng, Min Zhi-Chao, Hua Li-Xin, Feng Ning-Han, Yao Yong

Abstract excerpt

Interferon gamma (IFN-γ) plays a pivotal role in antiproliferative, antitumor and antiviral activities. The +874 polymorphism in IFN gene region reportedly affects cancer risk. However, pertinent studies offer conflicting results. To derive a more precise estimation, we performed a meta-analysis based on 1,929 cases and 2,830 controls from 17 published case-control studies, assessing the strength of the...

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Identifiers

PMID: 21127993
DOI: 10.1007/s11033-010-0575-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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