Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosis.

Scientific reports - 22 Oct 2022

Brankin Alice, Seifert Marva, Georghiou Sophia B, Walker Timothy M, Uplekar Swapna, Suresh Anita, Colman Rebecca E

Abstract excerpt

Universal drug susceptibility testing (DST) for tuberculosis is a major goal of the END TB strategy. PCR-based molecular diagnostic tests have been instrumental in increasing DST globally and several assays have now been endorsed by the World Health Organization (WHO) for use in the diagnosis of drug resistance. These endorsed assays, however, each interrogate a limited number of mutations associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amikacin
Share to Isoniazid
Share to Levofloxacin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Moxifloxacin

Share to Pyrazinamide

Share to Rifampin

Share to Tuberculosis, Multidrug-Resistant

Share to World Health Organization

Source

Open in PubMed Open full text

Identifiers

PMID: 36273016
DOI: 10.1038/s41598-022-21025-6
PMCID: PMC9587982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosis.PMID 36273016Read ↗

In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosisSemantic proximity Read ↗

Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance studySemantic proximity Read ↗

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement.Semantic proximity Read ↗

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.Semantic proximity Read ↗

Decoding antibiotic resistance in tuberculosis: Role of RRDR and non-RRDR mutations in diagnostic perspectives.Semantic proximity Read ↗

Rapid Identification of Drug Resistance and Phylogeny in M. tuberculosis, Directly from Sputum SamplesSemantic proximity Read ↗

Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.Semantic proximity Read ↗

Direct detection of drug-resistant Mycobacterium tuberculosis using targeted next generation sequencingSemantic proximity Read ↗

Clinical implications of molecular drug resistance testing for <I>Mycobacterium tuberculosis</I>: a TBNET/RESIST-TB consensus statementSemantic proximity Read ↗

Exploring diagnostic methods for drug-resistant tuberculosis: A comprehensive overview.Semantic proximity Read ↗

Exploring Diagnostic Methods for Drug-Resistant Tuberculosis: A Comprehensive OverviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.