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Article

Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation.

Circulation. Cardiovascular genetics - 1 Dec 2017

Hsueh Wen-Chi, Nair Anup K, Kobes Sayuko, Chen Peng, Göring Harald H H, Pollin Toni I, Malhotra Alka, Knowler William C, Baier Leslie J, Hanson Robert L

Abstract excerpt

BACKGROUND: Identity-by-descent mapping using empirical estimates of identity-by-descent allele sharing may be useful for studies of complex traits in founder populations, where hidden relationships may augment the inherent genetic information that can be used for localization. METHODS AND RESULTS: Through identity-by-descent mapping, using ≈400 000 single-nucleotide polymorphisms (SNPs), of serum lipid profiles,...

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Share to Apolipoprotein A-V
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

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Source

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Identifiers

PMID: 29237685
DOI: 10.1161/CIRCGENETICS.117.001809
PMCID: PMC5736502

Genes

APOA5
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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