Article
Evaluation of seven common lipid associated loci in a large Indian sib pair study.
Lipids in health and disease - 14 Nov 2012
Rafiq Sajjad, Venkata Kranthi Kumar M, Gupta Vipin, Vinay D G, Spurgeon Charles J, Parameshwaran Smitha, Madana Sandeep N, Kinra Sanjay, Bowen Liza, Timpson Nicholas J, Smith George Davey, Dudbridge Frank, Prabhakaran Dorairaj, Ben-Shlomo Yoav, Reddy K Srinath, Ebrahim Shah, Chandak Giriraj R
Abstract excerpt
BACKGROUND: Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is important since it would suggest wider relevance for these findings. Given the rising prevalence of metabolic disorders and heart disease in the Indian sub-continent, these studies could be of future...
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