Article
Non-malignant epithelial cells preferentially proliferate from nasopharyngeal carcinoma biopsy cultured under conditionally reprogrammed conditions.
Scientific reports - 12 Dec 2017
Yu Fenggang, Lu Yanan, Tao Lin, Jiang Yan-Yi, Lin De-Chen, Wang Lingzhi, Petersson Fredrik, Yoshiyama Hironori, Koeffler Phillip H, Goh Boon-Cher, Loh Kwok Seng
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is an invasive cancer with particularly high incidence in Southern China and Southeast Asia. The study of NPC is greatly hampered by the lack of reliable cell lines due to the loss of EBV genome and HeLa cell contamination. Conditional reprogramming (CR) cell culture technique has been reported for rapid and efficient establishment of patient-derived normal and tumor cell cultures....
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