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Article

Importance of Core Genome Functions for an Extreme Antibiotic Resistance Trait.

mBio - 12 Dec 2017

Gallagher Larry A, Lee Samuel A, Manoil Colin

Abstract excerpt

Extreme antibiotic resistance in bacteria is associated with the expression of powerful inactivating enzymes and other functions encoded in accessory genomic elements. The contribution of core genome processes to high-level resistance in such bacteria has been unclear. In the work reported here, we evaluated the relative importance of core and accessory functions for high-level resistance to the aminoglycoside...

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Identifiers

PMID: 29233894
DOI: 10.1128/mBio.01655-17
PMCID: PMC5727411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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