Article
genetic determinants of intrinsic colistin tolerance in Acinetobacter baumannii.
Infection and immunity - 1 Feb 2013
Hood M Indriati, Becker Kyle W, Roux Christelle M, Dunman Paul M, Skaar Eric P
Abstract excerpt
Acinetobacter baumannii is a leading cause of multidrug-resistant infections worldwide. This organism poses a particular challenge due to its ability to acquire resistance to new antibiotics through adaptation or mutation. This study was undertaken to determine the mechanisms governing the adaptability of A. baumannii to the antibiotic colistin. Screening of a transposon mutant library identified over 30 genes...
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