Article
Relationship between Escherichia coli growth rate and bacterial susceptibility to ciprofloxacin.
FEMS microbiology letters - 1 Jan 2018
Smirnova Galina V, Oktyabrsky Oleg N
Abstract excerpt
The effect of Escherichia coli growth rate on its susceptibility to ciprofloxacin was investigated using bacteria grown on different carbon sources and harboring mutations in genes encoding tricarboxylic acid cycle enzymes. A 1-h treatment of the wild type (wt) grown on glucose, succinate, malate, α-ketoglutarate or acetate with 0.3 μg ml-1 ciprofloxacin decreased the number of surviving cells (CFU ml-1), 560,...
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