Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simple and Rapid Tissue Clearing Method for Three-Dimensional Histology of the Pancreas.

Current protocols in cell biology - 11 Dec 2017

Wong Hang Sheung, Yeung Patrick Ka Kit, Lai Hei Ming, Lam Karen Siu Ling, Wutian Wu, Chung Sookja Kim

Abstract excerpt

Previously, high-resolution three-dimensional imaging of a whole and intact pancreas was not possible, since light is scattered when it passes through cell compartments with different refractive indices. CLARITY is one of the tissue clearing techniques that has yielded success with the central nervous system. To preserve tissue integrity after delipidation, conventional protocols embed tissue in an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice, Knockout
Share to Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Imaging, Three-Dimensional

Share to Insulin

Share to Lipids

Share to Pancreas

Share to Promoter Regions, Genetic

Share to Tissue Fixation

Source

Identifiers

PMID: 29227554
DOI: 10.1002/cpcb.34

Genes

MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simple and Rapid Tissue Clearing Method for Three-Dimensional Histology of the Pancreas.PMID 29227554Read ↗

Cellular and Molecular Probing of Intact Transparent Human OrgansSemantic proximity Read ↗

Simplified three-dimensional tissue clearing and incorporation of colorimetric phenotyping.Semantic proximity Read ↗

Optimizing Tissue Clearing Methods for Improved Imaging of Whole-Mount RetinasSemantic proximity Read ↗

Single-cell phenotyping within transparent intact tissue through whole-body clearing.Semantic proximity Read ↗

ADAPT-3D: Accelerated Deep Adaptable Processing of Tissue for 3-Dimensional Fluorescence Tissue Imaging for Research and Clinical SettingsSemantic proximity Read ↗

Lepr(db) mouse model of type 2 diabetes: pancreatic islet isolation and live-cell 2-photon imaging of intact islets.Semantic proximity Read ↗

Real‐time imaging of the pancreas during development of diabetesSemantic proximity Read ↗

High-Resolution 3D Fluorescent Imaging of Intact TissuesSemantic proximity Read ↗

Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease.Semantic proximity Read ↗

Deep tissue optical 3D imaging reveals preferential preservation of extra-islet β-cells in late-onset Type 1 DiabetesSemantic proximity Read ↗

Phenotyping Intact Mouse Bones Using Bone CLARITY.Semantic proximity Read ↗

Illuminating the complete ß-cell mass of the human pancreas - signifying a new view on the islets of LangerhansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.