Single Immunoglobulin IL-1-Related Receptor (SIGIRR) Gene rs7396562 Polymorphism and Expression Level in Rheumatoid Arthritis.

doi:10.1155/2021/6683148

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Article

Single Immunoglobulin IL-1-Related Receptor (SIGIRR) Gene rs7396562 Polymorphism and Expression Level in Rheumatoid Arthritis.

BioMed research international - 1 Jan 2021

Yang Xiaoke, Zhang Mingyue, Xu Shengqian, Pan Haifeng, Leng Ruixue, Shuai Zongwen

Abstract excerpt

OBJECTIVES: The aim of our study was to investigate the association of single-nucleotide polymorphism (SNP) and mRNA expression profile of single immunoglobulin IL-1-related receptor (SIGIRR) in rheumatoid arthritis (RA) in a Chinese population. METHODS: SIGIRR rs7396562 polymorphism was genotyped using TaqMan allelic discrimination assay in 517 RA patients and 601 healthy controls. Simultaneously, the SIGIRR...

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PMID: 34036103
DOI: 10.1155/2021/6683148
PMCID: PMC8124000

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