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Article

Zc3h10 is a novel mitochondrial regulator.

EMBO reports - 1 Apr 2018

Audano Matteo, Pedretti Silvia, Cermenati Gaia, Brioschi Elisabetta, Diaferia Giuseppe Riccardo, Ghisletti Serena, Cuomo Alessandro, Bonaldi Tiziana, Salerno Franco, Mora Marina, Grigore Liliana, Garlaschelli Katia, Baragetti Andrea, Bonacina Fabrizia, Catapano Alberico Luigi, Norata Giuseppe Danilo, Crestani Maurizio, Caruso Donatella, Saez Enrique, De Fabiani Emma, Mitro Nico

Abstract excerpt

Mitochondria are the energy-generating hubs of the cell. In spite of considerable advances, our understanding of the factors that regulate the molecular circuits that govern mitochondrial function remains incomplete. Using a genome-wide functional screen, we identify the poorly characterized protein Zinc finger CCCH-type containing 10 (Zc3h10) as regulator of mitochondrial physiology. We show that Zc3h10 is...

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Identifiers

PMID: 29507079
DOI: 10.15252/embr.201745531
PMCID: PMC5891430

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