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Article

High Prevalence of Rare Monogenic Forms of Obesity in Obese Guadeloupean Afro-Caribbean Children.

The Journal of clinical endocrinology and metabolism - 1 Feb 2018

Foucan Lydia, Larifla Laurent, Durand Emmanuelle, Rambhojan Christine, Armand Christophe, Michel Carl-Thony, Billy Rachel, Dhennin Véronique, De Graeve Franck, Rabearivelo Iandry, Sand Olivier, Lacorte Jean-Marc, Froguel Philippe, Bonnefond Amélie

Abstract excerpt

Context: The population of Guadeloupe Island exhibits a high prevalence of obesity. Objective: We aimed to investigate whether rare genetic mutations in genes involved in monogenic obesity (or diabetes) might be causal in this population of Afro-Caribbean ancestry. Design and Setting: This was a secondary analysis of a study on obesity conducted in schoolchildren from Guadeloupe in 2013 that aimed to assess...

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Identifiers

PMID: 29216354
DOI: 10.1210/jc.2017-01956

Genes

SIM1
ABCC8
KCNJ11
NTRK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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