Differential Effect of Polymorphisms on Body Mass Index Across the Life Course of Japanese: The Japan Multi-Institutional Collaborative Cohort Study.

doi:10.2188/jea.JE20190296

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Differential Effect of Polymorphisms on Body Mass Index Across the Life Course of Japanese: The Japan Multi-Institutional Collaborative Cohort Study.

Journal of epidemiology - 5 Mar 2021

Iwase Madoka, Matsuo Keitaro, Nakatochi Masahiro, Oze Isao, Ito Hidemi, Koyanagi Yuriko, Ugai Tomotaka, Kasugai Yumiko, Hishida Asahi, Takeuchi Kenji, Okada Rieko, Kubo Yoko, Shimanoe Chisato, Tanaka Keitaro, Ikezaki Hiroaki, Murata Masayuki, Takezaki Toshiro, Nishimoto Daisaku, Kuriyama Nagato, Ozaki Etsuko, Suzuki Sadao, Watanabe Miki, Mikami Haruo, Nakamura Yohko, Uemura Hirokazu, Katsuura-Kamano Sakurako, Kuriki Kiyonori, Kita Yoshikuni, Takashima Naoyuki, Nagino Masato, Momozawa Yukihide, Kubo Michiaki, Wakai Kenji

Abstract excerpt

BACKGROUND: Obesity is a reported risk factor for various health problems. Genome-wide association studies (GWASs) have identified numerous independent loci associated with body mass index (BMI). However, most of these have been focused on Europeans, and little evidence is available on the genetic effects across the life course of other ethnicities. METHODS: We conducted a cross-sectional study to examine the...

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PMID: 32147644
DOI: 10.2188/jea.JE20190296
PMCID: PMC7878711

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