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Article

Longitudinal association of a body mass index (BMI) genetic risk score with growth and BMI changes across the life course: The Cardiovascular Risk in Young Finns Study.

International journal of obesity (2005) - 1 Aug 2020

Buscot Marie-Jeanne, Wu Feitong, Juonala Markus, Lehtimäki Terho, Pitkänen Niina, Sabin Matthew A, Viikari Jorma S A, Raitakari Olli T, Magnussen Costan G

Abstract excerpt

BACKGROUND: The role of genetic risk scores associated with adult body mass index (BMI) on BMI levels across the life course is unclear. We examined if a 97 single nucleotide polymorphism weighted genetic risk score (wGRS97) associated with age-related progression in BMI at different life stages and distinct developmental trajectories of BMI across the early life course. METHODS: 2188 Cardiovascular Risk in Young...

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PMID: 32494039
DOI: 10.1038/s41366-020-0611-x

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