Article
Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip.
Nature biotechnology - 1 Sept 2018
Hassibi Arjang, Manickam Arun, Singh Rituraj, Bolouki Sara, Sinha Ruma, Jirage Kshama B, McDermott Mark W, Hassibi Babak, Vikalo Haris, Mazarei Gelareh, Pei Lei, Bousse Luc, Miller Mark, Heshami Mehrdad, Savage Michael P, Taylor Michael T, Gamini Nader, Wood Nicholas, Mantina Pallavi, Grogan Patrick, Kuimelis Peter, Savalia Piyush, Conradson Scott, Li Yuan, Meyer Rich B, Ku Edmond, Ebert Jessica, Pinsky Benjamin A, Dolganov Gregory, Van Tran, Johnson Kirsten A, Naraghi-Arani Pejman, Kuimelis Robert G, Schoolnik Gary
Abstract excerpt
The emergence of pathogens resistant to existing antimicrobial drugs is a growing worldwide health crisis that threatens a return to the pre-antibiotic era. To decrease the overuse of antibiotics, molecular diagnostics systems are needed that can rapidly identify pathogens in a clinical sample and determine the presence of mutations that confer drug resistance at the point of care. We developed a fully...
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