Article
Homeodomain-interacting protein kinase promotes tumorigenesis and metastatic cell behavior.
Disease models & mechanisms - 17 Jan 2018
Blaquiere Jessica A, Wong Kenneth Kin Lam, Kinsey Stephen D, Wu Jin, Verheyen Esther M
Abstract excerpt
Aberrations in signaling pathways that regulate tissue growth often lead to tumorigenesis. Homeodomain-interacting protein kinase (Hipk) family members are reported to have distinct and contradictory effects on cell proliferation and tissue growth. From these studies, it is clear that much remains to be learned about the roles of Hipk family protein kinases in proliferation and cell behavior. Previous work has...
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