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Article

HIPK1 drives p53 activation to limit colorectal cancer cell growth

15 Jun 2013

Abstract excerpt

HIPK1 (homeodomain interacting protein kinase 1) is a serine/threonine kinase that belongs to the CMGC superfamily. Emerging data point to the role of HIPK1 in cancer, but it is still not clear whether it acts as a tumor suppressor or promoter. Here we identified HIPK1 as a kinase that is significantly overexpressed in colorectal cancer (CRC) and whose expression is stage-dependent. Being abundantly expressed at...

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Identifiers

PMID: 23676219
DOI: 10.4161/cc.24927

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