Article
Bayesian analysis of genome-wide inflammatory bowel disease data sets reveals new risk loci.
European journal of human genetics : EJHG - 1 Feb 2018
Zhang Yu, Tian Lifeng, Sleiman Patrick, Ghosh Soumitra, Hakonarson Hakon
Abstract excerpt
Genome-wide association studies (GWAS) have identified and validated 200 risk loci for inflammatory bowel disease (IBD) to date, including risk loci for both Crohn's disease and ulcerative colitis. Previously studies mainly used single SNP testing methods and only reported the most significant association within each locus. Advanced methods are needed to detect additional joint effects of multiple SNPs and fine...
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