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Article

Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes.

Scientific reports - 4 Dec 2017

Zhang Jushan, Peng Shouneng, Cheng Haoxiang, Nomura Yoko, Di Narzo Antonio Fabio, Hao Ke

Abstract excerpt

Smoking is a major cause of respiratory conditions. To date, the genetic pleiotropy between smoking behavior and lung function/chronic obstructive pulmonary disease (COPD) have not been systematically explored. We leverage large data sets of smoking behavior, lung function and COPD, and addressed two questions, (1) whether the genetic predisposition of nicotine dependence influence COPD risk and lung function;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29203782
DOI: 10.1038/s41598-017-16964-4
PMCID: PMC5715160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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