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Article

The clinical and prognostic relevance of driver mutations in 203 Taiwanese patients with primary myelofibrosis.

Journal of clinical pathology - 1 Jun 2018

Kuo Ming-Chung, Lin Tung-Huei, Sun Chien-Feng, Lin Tung-Liang, Wu Jin-Hou, Wang Po-Nan, Huang Ying-Jung, Chang Hung, Huang Ting-Yu, Shih Lee-Yung

Abstract excerpt

AIMS: We investigated the clinical and prognostic relevance of the mutational status of driver genes with allele burden and endogenous erythroid colony (EEC) growth in 203 Taiwanese patients with primary myelofibrosis (PMF). METHODS: Pyrosequencing was used to detect JAK2V617F mutational status and measure allele burden, while MPL (exon 10) mutations were analysed by PCR assay and then by direct sequencing. CALR...

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Source

Identifiers

PMID: 29203554
DOI: 10.1136/jclinpath-2017-204829

Genes

CALR
MPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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