Article
CALR mutation profile in Irish patients with myeloproliferative neoplasms.
Hematology/oncology and stem cell therapy - 1 Sept 2016
Haslam Karl, Conneally Eibhlin, Flynn Catherine M, Cahill Mary R, Gilligan Oonagh, O'Shea Derville, Langabeer Stephen E
Abstract excerpt
Insertion and/or deletion mutations of the CALR gene have recently been demonstrated to be the second most common driver mutations in the myeloproliferative neoplasms (MPNs) of essential thrombocythemia (ET) and primary myelofibrosis (PMF). Given the diagnostic and emerging prognostic significance of these mutations, in addition to the geographical heterogeneity reported, the incidence of CALR mutations was...
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