Article
JAK2, MPL, and CALR mutations in Chinese Han patients with essential thrombocythemia.
Hematology (Amsterdam, Netherlands) - 1 Apr 2017
Wang Jing, Zhang Biao, Chen Bing, Zhou Rong-Fu, Zhang Qi-Guo, Li Juan, Yang Yong-Gong, Zhou Min, Shao Xiao-Yan, Xu Yong, Xu Xi-Hui, Ouyang Jian, Xu Jingyan, Ye Qing
Abstract excerpt
BACKGROUND: Mutations in Janus kinase 2 (JAK2), myeloproliferative leukemia (MPL), and CALR are highly relevant to Philadelphia chromosome (Ph)-negative myeloproliferative neoplasms. METHODS: Assessing the prevalence of molecular mutations in Chinese Han patients with essential thrombocythemia (ET), and correlating their mutational profile with disease characteristics/phenotype. RESULTS: Of the 110 subjects...
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